Accurate. Timely. Trusted.

The premiere anatomic pathology laboratory
for Physician Offices, Hospitals, and Surgery/Endoscopy Centers.

Accurate. Timely. Trusted.

The premiere anatomic pathology laboratory
for Physician Offices, Hospitals, and Surgery/Endoscopy Centers.

Accurate. Timely. Trusted.

The premiere anatomic pathology laboratory
for Physician Offices, Hospitals, and Surgery/Endoscopy Centers.

Trusted By

Dedicated to Diagnostic Excellence

Get more precise diagnoses and better patient outcomes when you collaborate with our over 20 board-certified pathologists in 15+ medical subspecialties.

Divisions & Specialties

Breast Pathology



FNA Clinic

Gastrointestinal Pathology

General Surgical Pathology

Genitourinary Pathology

Gynecologic Pathology

Head & Neck Pathology



Oral Pathology

Pediatric Pathology

Renal Pathology

Pathology Reference Laboratory

Welcome to Pathology Reference Laboratory – celebrating over 100 years in Texas!

We are a clinical pathology lab in San Antonio, TX that offers comprehensive diagnostic testing services to hospitals and physicians. With a large team of pathologists and a wide range of expertise, we are equipped to handle even the most complex cases.

Our Services

We offer a wide range of anatomic and clinical pathology services, including molecular testing, cytology, histopathology, and more. We use the latest technology and techniques to provide accurate and timely results for our clients.

Our Expertise

Our team of pathologists has years of experience in diagnosing and treating a wide range of conditions, from common illnesses to rare diseases. We are dedicated to providing personalized care and solutions for each patient, and we work closely with hospitals and physicians to ensure the best possible outcomes.

Why Choose Us

Easy Shipping. Fast Turnaround. Always available for consultations.

At Pathology Reference Laboratory, we are committed to providing the highest quality of care and service to our clients. We are accredited by leading industry organizations, and we follow the highest standards for accuracy and reliability. With our advanced technology and expert team, we are able to provide fast and accurate results that help guide treatment decisions and improve patient outcomes.

Pathology Reference Lab is owned by physicians — you and your patients best interests are always a priority.

What is a Clinical Pathology Laboratory?

A clinical pathology laboratory is an integral part of healthcare. These laboratories are specialized facilities where biological samples are analyzed to diagnose various diseases and conditions. Clinical pathology laboratories provide valuable information and essential diagnostic services to physicians so they can give their patients an accurate diagnosis and provide appropriate treatments. 

The main function of a clinical pathology laboratory is to analyze and evaluate various biological samples, such as blood, urine, tissue, and other body fluids. The results from these tests help healthcare professionals diagnose and treat a wide range of illnesses and conditions.

Types of Tests Performed in a Clinical Pathology Laboratory

Clinical pathology laboratories conduct a variety of tests to determine the cause of a patient’s symptoms or to monitor the progress of treatment. Some of the most common tests performed in a clinical pathology laboratory include:

  • Hematology: This branch of pathology focuses on studying blood and its components, such as red and white blood cells, platelets, and plasma. Hematology tests are used to diagnose and monitor blood disorders, including anemia, leukemia, and clotting abnormalities.
  • Cytology and histology: Cytology examines individual cells, while histology analyzes the microscopic structure of tissues. Both techniques are essential for diagnosing and grading cancer and other diseases affecting tissues and organs.
  • Immunology: This field focuses on the immune system and its response to various antigens, including allergens, infectious agents, and tumor cells. Immunology tests can detect autoimmune disorders, allergies, and immune deficiencies.
  • Molecular diagnostics: These advanced tests use polymerase chain reaction (PCR) and gene sequencing techniques to analyze DNA and RNA in biological samples. Molecular diagnostics can detect genetic mutations, infectious agents, and certain types of cancer.
  • Microbiology: Microbiology tests identify and characterize microorganisms, such as bacteria, viruses, fungi, and parasites, that cause infections. These tests help healthcare providers determine the appropriate treatment for infectious diseases and monitor the effectiveness of antibiotic therapy.

The Importance of a Clinical Pathology Laboratory

A clinical pathology laboratory plays a crucial role in the healthcare system because it gives physicians the information they need to diagnose and treat their patients. Here are several ways a clinical pathology laboratory contributes to the healthcare ecosystem:

  • Accurate diagnosis: A correct diagnosis is the first step in managing any medical condition. Clinical pathology laboratories give healthcare providers the information they need to make accurate diagnoses and initiate appropriate treatment.
  • Monitoring treatment: Clinical pathology laboratories help healthcare providers monitor the progress of treatment by providing regular test results. This information is crucial for adjusting treatment plans and ensuring the best possible outcome for the patient.
  • Early detection and prevention: Many diseases can be effectively managed or even prevented if detected early. Clinical pathology laboratories play a pivotal role in identifying diseases in their early stages, allowing for prompt treatment and a higher likelihood of resolution.
  • Research and development: Clinical pathology laboratories contribute significantly to medical research by providing data and insights that drive the development of new diagnostic methods, treatments, and preventive measures.

A Clinical Pathology Laboratory Is a Part of the Healthcare Team

A clinical pathology laboratory, and the pathologists in them, are essential components of the healthcare team. They provide critical diagnostic services that can make all the difference in a patient’s care.  Having a trusted clinical pathology laboratory to work with you and your doctors can help ensure you’ll have the best care possible.